Rosuvastatin Vertex (other trade names - Crestor, Mertenil, Rosistark, Rosulip, Roxer, Tevastor) is a medication that helps to treat hypercholesterolemia - a pathological condition that leads to atherosclerosis and its associated diseases.
Rosuvastatin belongs to a group of medications witch are called statins.
Among all statins, Rosuvastatin is the most resarched, and have proven medical efficacy.
Rosuvastatin is used to correct the concentration of separated lipid fractions in body fluids and tissues.
Rosuvastatin reduces the density of Low density lipoprotein (LDL) particles and increases the density of High-density lipoproteins (HDL) particles.
Rosuvastatin reduces the size of atherosclerotic plaques and increased vascular lumen.
Also Rosuvastatin reduces the level of C-reactive protein.
The lipid-lowering action of Rosuvastatin is directly proportional to the amount of the prescribed dose.
- Primary hypercholesterolemia according to the classification of Fredrickson (type IIa, including familial heterozygous hypercholesterolemia) or mixed hypercholesterolemia (type IIb) as a supplement to the diet, when diet and other non-drug therapies (such as exercise, weight loss) are insufficient.
Family homozygous hypercholesterolemia as a supplement to diet and other lipid lowering therapy (for example, LDL apheresis), or in cases where such therapy is not effective enough.
- Hypertriglyceridemia (type IV according to the classification of Fredrickson) as an addition to the diet.
To slow the progression of atherosclerosis, as a supplement to the diet in patients who are shown therapy to reduce the concentration of total cholesterol and LDL-C.
- Primary prevention of major cardiovascular complications (stroke, heart attack, arterial revascularization) in adult patients without clinical signs of coronary heart disease (CHD), but with an increased risk of its development (over 50 years old for men and over 60 years old for women, increased concentration C-reactive protein (2 mg / L), in the presence of at least one of the additional risk factors, such as arterial hypertension, low concentration of HDL-C, smoking, family history of early onset of coronary artery disease.
Contraindications: there are numerous contraindications and side effects. Please consult with your treating doctor.