• Klacid-SR (Clarithromycin)  Prolonged Action 7 tabs 500 mg

Klacid-SR (Clarithromycin) is a semisynthetic macrolide antibiotic prolonged action, used to treat various bacterial infections, with bacteriostatic action. Klacid-SR (Clarithromycin) binds to the 50s-subunit of the bacterial ribosome, causing suppression of bacterial protein synthesis. Klacid-SR (Clarithromycin) acts mainly bacteriostatic, as well as bactericidal.

Klacid-SR (Clarithromycin) inhibits protein synthesis in a microbial cell and is active against:

  • gram-positive aerobic microorganisms - Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumonia, Listeria monocytogenes
  • aerobic gram-negative microorganisms - Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella (Branhamella) catarrhalis, Neisseria gonorrhoea, Legionella pneumophila, Helicobacter pylori
  • advantageously intracellular microorganisms - Mycoplasma pneumonia, Chlamydia pneumonia (TWAR), Mycobacterium leprae, Mycobacterium kansaii, Mycobacterium chelonae, Mycobacterium fortitum, Mycobacterium avium complex (MAC), Mycobacterium intracellulare.


In vitro, Klacid-SR (Clarithromycin) is active against most strains of the following microorganisms:

  • aerobic gram-positive microorganisms - Streptococcus agalactiae, Streptococci (groups C, F, G), Streptococcus viridans
  • aerobic gram-negative microorganisms - Bordetella pertussis, Pasteurella multocida, Campylobacter jejuni
  • anaerobic gram-positive microorganisms - Clostridium perfringens, Peptococcus niger, Propionibacterium acnes
  • anaerobic gram-negative microorganisms - Bacteroides melaninogenicus
  • spirochete - Borrelia burgdorferi, Treponema pallidum.

Klacid-SR (Clarithromycin) is well absorbed from the gastrointestinal tract. Eating slows down the absorption of Klacid (Clarithromycin), but does not affect the bioavailability of the active substance.

Approximately 20% of Klacid-SR (Clarithromycin) is immediately metabolized to form the main metabolite of 14-hydrochlorithromycin.

Indications:

  • lower respiratory tract infections (bronchitis, pneumonia)
  • upper respiratory tract infections (pharyngitis, sinusitis)
  • otitis
  • infections of the skin and soft tissues (folliculitis, cellulitis, erysipelas)
  • common mycobacterial infections caused by Mycobacterium avium and Mycobacterium intracellulare
  • localized mycobacterial infections caused by Mycobacterium chelonae, Mycobacterium fortuitum and Mycobacterium kansasii
  • Helicobacter pylori eradication and a decrease in the frequency of relapse of a duodenal ulcer
  •  Lyme disease
  • prevention of the spread of infection due to the Mycobacterium avium complex (MAC) complex in HIV-infected patients with a CD4 lymphocyte count (T-helper lymphocytes) of not more than 100 in 1 mm3
  • odontogenic infections.

 Contraindications:

  • severe liver dysfunction
  • severe renal impairment (CC <30 ml / min)
  • porphyria
  • simultaneous use with astemizole, cisapride, pimozide, terfenadine, ergotamine, dihydroergotamine
  • pregnancy, lactation (breastfeeding)
  • children's age up to 3 years (when using tablets)
  • hypersensitivity to antibiotics of the macrolide group.

Klacid-SR (Clarithromycin) should be used with caution in patients with impaired liver and kidney function.

 

CAS Number: 81103-11-9 

Package: 14 tabs 500 mg.

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Klacid-SR (Clarithromycin) Prolonged Action 7 tabs 500 mg

  • Brand: AbbVie s.r.l.
  • Product Code: Klacid-SR (Clarithromycin) - 7 tabs 500 mg
  • Availability: In Stock
  • Klacid-SR (Clarithromycin) Prolonged Action 7 tabs 500 mg>

    $16.99


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Tags: antibiotic, clarithromycin, macrolide